Each capsule of Mega
Benfotiamine contains vitamin C 10 mg and Benfotiamine 250 mg. Other
ingredients: calcium carbonate, microcrystalline cellulose, vegetable
capsule, silica, magnesium stearate.
According to the manufacturer:
Reprinted with permission of Life Extension.
"Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports
healthy blood sugar metabolism and helps protect the body's tissues
against advanced glycation end products and oxidative stress.13 For
example, the enzyme transketolase is critical to blood sugar metabolism.
Like many enzymes, transketolase requires a co-factor. In this case, it
needs assistance from thiamine. Unfortunately, thiamine is
water-soluble, which makes it less available to the interior of the
cell. Benfotiamine is fat-soluble and can easily penetrate into the
inside of cells. It is also more bioavailable than the water-soluble
thiamine.
In a landmark study, benfotiamine effectively increased transketolase
activity in cell cultures by an astounding 300%, compared to a mere 20%
for thiamine. This robust activation was sufficient to block three of
the four major metabolic pathways leading to blood vessel damage.14
Benfotiamine also blocks the activation of the transcription factor
known as nuclear factor-kappa B (NF-kB), which is implicated in numerous
inflammatory conditions.13
Overall, benfotiamine can activate glucose metabolism and promote
already healthy blood glucose levels. It can also reduce formation of
advanced glycation end products to prevent glucose toxicity and correct
endothelial cell defects caused by high concentrations of blood glucose,
especially inside endothelial, retinal, kidney and nerve cells.
Benfotiamine also helps maintain healthy endothelial function.15-21
Benfotiamine with thiamine is a low-cost dietary supplement that can
help maintain already-normal blood sugar levels and support the health
of the nerves, kidneys, eyes, blood vessels, and heart."
The manufacturer prohibits further discount of this product.
