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WHAT IS IT?

Ribose is D-Ribose, a simple sugar.  A jar of powder contains 250 grams. Each scoop contains 2.2 grams. There are 113 scoops per jar.

WHAT DOES IT DO?

Over 150 studies demonstrate the ability of ribose, a pentose sugar found in all living cells, to increase adenosine triphosphate (ATP) levels and total adenine nucleotide (TAN) recovery, promoting skeletal and cardiac muscle energy metabolism.  Ribose is the key compound used by the body to form the nucleotides AMP, ADP and ATP, which are depleted during strenuous physical activity or from lack of oxygen.  Skeletal and cardiac muscle rely on these metabolites for energy, and two metabolic pathways preserve these pools.  The first mechanism involves salvaging end products of AMP breakdown, or preventing them from leaving the cell.  If they are salvaged, they may be recycled back to AMP and ultimately to ATP.  The second mechanism for preserving nucleotide pools is de novo synthesis, or formation of new nucleotides from ribose.  Both of these crucial activities can only begin when ribose is converted to 5-phosphoribosyl-1-pyrophosphate (PRPP).  If ribose concentrations are not sufficient, PRPP is in low supply and muscle cells cannot adequately recharge.  Although the body has the ability to manufacture ribose from glucose, it is a slow process which requires glucose-6-phosphate dehydrogenase (G-6-PDH), an enzyme typically in short supply.  Supplemental ribose allows the body to bypass this step, rapidly supplying the compounds needed to boost salvage and enhance de novo synthesis.  Research indicates that nucleotides decrease after repeated, intense exercise and that they may not be recovered for up to several days, leaving muscle without the ability to refuel energy stores.  Ribose also offers powerful, complementary support to creatine by enhancing TAN pools, providing the necessary substrates which creatine can then convert to ATP.

Ribose, taken before, during or after high-intensity exercise, accelerates replenishment of depleted adenine nucleotide pools, keeping ATP and TAN levels at their peak, and providing rapid regeneration of critical energy molecules for maximal training.  
 

CAUTIONS

D-Ribose is non-toxic. Diarrhea has occurred in people taking experimentally high doses of 60 grams or more per day. Theoretically, it can lower blood sugar and should be used with caution by diabetics.

D-Ribose is hygroscopic (absorbs water from the air) so keep the lid on tight.

See Disclaimer.

DOSE

Take 1-2 scoops per day, 30 minutes before or following an exercise session, or in divided doses before and after exercise.  On days with no exercise scheduled, take in the evening before bedtime. Being a sugar it has a slightly sweet taste.

NHC sells 250 gram jars of Ribose powder for $71.55. The suggested retail price is $79.50.

CI

These statements have not been evaluated by the U.S. Food & Drug Administration (FDA).
The products discussed are not intended to diagnose, treat, cure, or prevent any disease.
 

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Created  March 1, 1998 (Personal page April 25, 1995)
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Gerry Wolke, RPh.