888 852-4993

by Life Extension

WHAT IS IT?

Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-, but only the methyl form is used in the central nervous system. Deficiency states are fairly common and vitamin B12 deficiency mimics many other disease states of a neurological or psychological kind, and it causes anemia.  Cyanocobalamin (the kind in vitamin supplements) is converted by the liver into methylcobalamin but not in therapeutically significant amounts. Vitamin B12 deficiency is caused by a wide range of factors including low gastric acidity (common in older people,) use of acid blockers such as Prilosec™ or excessive laxative use, lack of intrinsic factor, poor aborption from the intestines, lack of Calcium, heavy metal toxicity, or excessive Vitamin B12 degradation.

Each sublingual lozenge contains 1 mg or 5 mg of methylcobalamin. Inert ingredients include sorbitol, mannitol, cellulose, vanilla flavor, magnesium stearate, croscarmellose sodium, and silica.

WHAT DOES IT DO?

According to the manufacturer:

"Methylcobalamin is the form of vitamin B12 active in the central nervous system. It is an active coenzyme of the vitamin B12 analogs, that is essential for cell growth and replication. The liver may not convert cyanocobalamin, the common supplemental form of vitamin B12, into adequate amounts of methylcobalamin the body may need for proper neuronal functioning. Methylcobalamin may exert its neuroprotective effects through enhanced methylation, acceleration of nerve cell growth, or its ability to promote healthy homocysteine levels. For methylcobalamin to be available to the brain, it should be allowed to dissolve under the tongue."
 

CAUTIONS

None.

See Disclaimer.

DOSE

For every day prevention take 1 mg daily under the tongue. Specific conditions may require higher doses up to 40 mg.

NHC sells bottles of 60 lozenges of Methylcobalamin 1 mg for $7.45. The suggested retail price is $9.95

NHC also sells bottles of 60 lozenges of Methylcobalamin 5 mg for $24.00. The suggested retail price is $32.00.

CR I

These statements have not been evaluated by the U.S. Food & Drug Administration (FDA).
The products discussed are not intended to diagnose, treat, cure, or prevent any disease.
 

Created  March 1, 1998 (Personal page April 25, 1995)
(This site was created from FrontPage 2000 at a resolution of 1024x768 in 32 bit color on a 19 inch monitor. It was checked using Microsoft IE 5.0. Your results may vary depending upon your browser, monitor, and color resolution.) Updated on May 25, 2003.
Gerry Wolke, RPh.