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by Cognitive Nutrition (90,180)

Complementary Prescriptions (45)

WHAT IS IT?

Idebenone is an analogue of Coenzyme Q10. Each capsule contains 45 mg, 90 mg or 180 mg. Other inert ingredients for 90 and 180 mg strength include maltodextrin or soy fiber, gelatin capsule.

Other inert ingredients for 45 mg strength include Microcrystalline cellulose and Hydroxypropyl
methylcellulose (Vcap).

WHAT DOES IT DO?

In most respects, Idebenone shares its traits with Coenzyme Q10. It differs from it in some important ways which may make it more useful.

Under certain circumstances, Coenzyme Q10 (CoQ10) may become a pro-oxidant. These circumstances are conditions in which hypoxia or lack of oxygen occurs. In cases of shock, heart attack, stroke, or poor circulation, CoQ10 auto-oxidizes and unleashes massive amounts of various free radicals which damage delicate tissues and because CoQ10 is necessary for electron transport and ATP (energy currency) production, cellular death may ensue. Idebenone, on the other hand, suppresses free radicals and continues ATP production in hypoxic situations. This may make it a useful supplement for individuals at risk for those conditions.

Another important trait of Idebenone not shared by CoQ10 include the ability to raise the brain's serotonin levels.

According to the manufacturer (Cognitive Nutrition):

"Idebendone increases brain levels of nerve growth factor.

It elevates cerebral serotonin and acetylcholine levels (mood and memory support.)

It's a potent mitochondrial antioxidant.

It enhances long-term potentiation (LTP) in the hippocampus (enhances long term memory.)"

CAUTIONS

Few adverse reactions have been noted with this substance even at doses of 900 mg per day. Nausea, increased hepatic enzymes, headache, dizziness, and bronchitis, all mild relative to placebo taking groups and reversible.

See the Disclaimer.

DOSE

Take one to 4 capsules daily with meals or as directed by your health practitioner. It is best taken with a fatty substance.

NHC sells bottles of 60 capsules of Idebenone 45 mg for $32.35. The suggested retail price is $35.95.

NHC sells bottles of 60 capsules of Idebenone 90 mg for $22.95 The suggested retail price is $29.99.

NHC sells bottles of 60 capsules of Idebenone 180 mg for $42.95. The suggested retail price is $54.99.

CR I

These statements have not been evaluated by the U.S. Food & Drug Administration (FDA).
The products discussed are not intended to diagnose, treat, cure, or prevent any disease.
 

Created  March 1, 1998 (Personal page April 25, 1995)
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Gerry Wolke, RPh.