Endothelial Defense with Full Spectrum Pomegranate
by Life Extension
WHAT IS IT?
Each 2 vegetarian capsules of Endothelial Defense with Full Spectrum Pomegranate contains:
- Superoxide Dismutase/Gliadin Complex (GliSODin) [SOD (Superoxide Dismutase) Enzyme Activity = 500 IU] 500 mg
- Pomella Pomegranate (Punica granatum) Extract (fruit) [std. to 30% Punicalagins (120 mg)] 400 mg
- Pomegranate (Punica granatum) 5:1 Extract (fruit) 100 mg
- PomComplete Pomegranate (Punica granatum) Blend [flower extract and seed oil (standardized to 22% (30 mg) punicic acid)] 137.5 mg
- Other ingredients: soybean oil, maltodextrin, gelatin, glycerin, purified water, caramel color, beeswax, phosphatidylcholine. Contains soybeans, tree nuts (cocoa beans) and wheat. Contains gluten.
WHAT DOES IT DO?
According to the manufacturer:
Reprinted with permission of Life Extension.
The endothelium is the inner lining of the blood vessel that regulates arterial health. Maintaining its youthful integrity supports overall cardiovascular health as humans age.
Endothelial Defense with Full-Spectrum Pomegranate supplies standardized pomegranate and an orally active form of superoxide dismutase to support endothelial health. Both of these components (pomegranate, SOD) have been clinically shown to help with blood flow and age-related changes in endothelial function.2-8
1.Pomegranate supports healthy blood flow. In a group of aging humans with risk factors for cardiovascular events, pomegranate or placebo was ingested on a daily basis. After 12 months, the mean intima media thickening improved 44% in the pomegranate group, whereas carotid blood flow worsened by 9% in the placebo group.2 Both groups continued taking conventionally prescribed medications. In another study on patients with ischemic coronary heart disease, pomegranate or placebo was ingested daily. After only three months, coronary artery blood flow improved by 18% in the pomegranate group, but worsened by 17% in the placebo group.2 A standardized pomegranate extract is one of the active components of Endothelial Defense.
2.SOD protects against nitric oxide degradation. Aging results in a reduction of our body's production of the critical antioxidant called superoxide dismutase (SOD). One consequence of SOD depletion is excess degradation of endothelial nitric oxide. An orally active superoxide dismutase called GliSODin has been clinically shown to support healthy arterial function and structure, while boosting levels of the body's most powerful antioxidant enzymes (SOD and catalase).4-7 Studies show that carotid artery thickness increases by 0.04 mm every 10 years. However, a 2007 GliSODin study suggested that 2.8 years of supplementation may turn back the clock on 10 years of age-related changes due to carotid artery wall thickening.6 Endothelial Defense contains the patented GliSODin in the identical dose.
3.Pomegranate flower extract and seed oil blend. This blend of pomegranate flower extract and seed oil contains potent polyphenols that provide support for youthful lipid and glucose metabolism and help with inflammatory factors.8
CAUTIONS
If pregnant or breast feeding ask a health care professional before use. Do not take if you are allergic to wheat or gluten. Consult with your physician before using this product if you are taking anti-seizure, anti-depressant or psychiatric medications, or certain types of blood pressure (e.g. calcium channel blockers) medications.
See
Disclaimer.
DOSE
Take two capsules daily before breakfast, or as recommended by a healthcare practitioner.
NHC sells 60 capsule bottles of Endothelial Defense with Full Spectrum Pomegranate for
$42.00. The suggested retail price is $56.00. The manufacturer prohibits further discount of this product.
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